Advancing core workflows with the Intabio ZT system

Advancing core workflows with the Intabio ZT system

Event Overview:

Thu, Nov 7, 2024 11:00 AM EDT

Characterization of charge isoforms, whether in early product development or associated with licensure filings, is usually achieved through separate analytical techniques. Fraction collection via ion-exchange (IEX) liquid chromatography or iCE followed by mass spectrometry are typically used.

This webinar discusses opportunities to advance core platform technologies through a fully integrated icIEF-UV/MS workflow on the Intabio ZT system and how rapid post-translational modification (PTM) characterization of charge isoforms can be used to guide decisions during early development.

Key Learning Objectives:

• Identify sequence variants with icIEF-UV/MS
• Identify charge variants of AAVs with icIEF-UV/MS
• Incorporate icIEF-UV/MS into existing standard operating procedures
• Understand the impact rapid charge variant identification has on drug development

Who Should Attend:

• Analytical development scientists
• Process development scientists
• Cell line development scientists
• Protein characterization scientists

Featured Speakers

Kristen Nields, PhD

Principal Scientist Johnson & Johnson Innovative Medicine

Xiaoping He, PhD

Principal Scientist Pfizer

For any technical questions please contact David Ambrose: Dambrose@mjhlifesciences.com

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